The International Severe Acute Respiratory Infection Coronavirus Clinical Characterisation Consortium (ISARIC 4C) is a UK-wide consortium of doctors and scientists committed to answering urgent questions about COVID-19. The ISARIC Clinical Characterisation Protocol (CCP) aims to study COVID-19 disease to better understand its spread and behaviour by analysing biological samples and data from patients with confirmed […]
DiagnosticInformatics ApproachesPreventionTherapeutic Clinical description and outcome of hospitalised COVID-19 patients
Clinical characteristics and outcomes for hospitalised COVID-19 patients in the UK are important to guide the national response to this pandemic and emerging evidence suggests ethnic minorities might be disproportionately affected. Imperial researchers undertook a retrospective cohort study to characterise the main risk factors associated with in-hospital deaths on patients hospitalised with laboratory-confirmed SARS-CoV-2 infection […]
Convalescent plasma is the antibody-rich plasma of someone who has recovered from a virus. The plasma may contain antibodies that their immune system has produced in fighting the virus – in this case, COVID-19, which can then be transfused into infected patients whose immune systems are struggling to fight the infection. The REMAP-CAP trial is […]
Established in 2013, and part of Imperial College London, the NIHR London In Vitro Diagnostics has a strong track record working with innovators to enable evidence generations, supporting market adoption. They do this by working closely with clinicians within healthcare settings and through partnerships with world-class technologists, scientists and methodologists. In response to the COVID-19 […]
Imperial’s Clinical Analytics, Research and Evaluation (iCARE) project started as a proof of concept high performance analytics environment, funded by NIHR Imperial BRC, in Autumn 2019. In collaboration with UKCloud and Bluemetrix, the NIHR Imperial BRC have set up a high performance, cloud-based, informatics solution that will allow NHS Trust staff to access de-identified data […]
NIHR Imperial BRC have set up a high performance, cloud-based, informatics solution that will allow NHS Trust staff to access de-identified data to improve patient care. Find out more here.
To accelerate our understanding and response to coronavirus, a COVID-19 specific de-identified dataset was created, pulling together data from Imperial College Healthcare NHS Trust and the region’s linked longitudinal dataset. Find out how to get access here.
NIHR Imperial BRC has established a new ‘virtual’ Theme, with the aim of acting as a focal and coordinating point for all the active and proposed research initiatives currently being directed towards the diagnosis and treatment of COVID-19 infection. Find out more about ongoing activities here.
Examples of research projects testing out new drugs, devices and diagnostics in humans for the first time. The BRC is specifically aimed at supporting these kinds of experimental medicine studies.
The NIHR Imperial BRC has developed a range of innovative device technologies, in collaboration with scientists in our Faculties of Natural Sciences and Engineering. Some of the most recent are highlighted here.
The NIHR Imperial BRC has a strong, successful track record of collaborating with life sciences and other related industries, academic institutions, charities and research organisations. Most recent examples can be found here.