The NIHR Imperial BRC provides funding to underpin a wide variety of experimental medicine facilities, technology platforms and core supporting services. Most notably the BRC invests significantly in four Cross-Cutting Themes, which provide cutting edge technologies but which also conduct research programmes in their own right.
In our Informatics & Biobanking Theme we bring together bioinformatics, data engineering and health informatics capabilities with large-scale human tissue and sample collections, linked via a secure research data warehouse to the Trust’s electronic patient record system. The Theme incorporates the Imperial Tissue Bank led by Professor Gerry Thomas.
The Genetics & Genomics Theme provides a ‘one-stop-shop’ for next generation sequencing (NGS) of human genomes and microarray technology in the Imperial BRC Genomics Facility. The Theme also includes access to bioinformatics capabilities in support of NGS, data storage and sample preparation capacity.
In the Molecular Phenomics Theme, the BRC supports considerable capacity in high throughput mass spectroscopy and nuclear magnetic resonance (NMR) analysis, with state-of-the-art bioinformatics, in order to differentiate and quantify metabonomic markers. The Clinical Phenotyping Centre aims to provide doctors with better information at each stage of a patient’s treatment, helping them diagnose illness more efficiently and choose the best treatments based on a patient’s individual metabolic and physiological characteristics.
The Imaging Theme provides access to state-of-the-art X-ray, ultrasound, Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) through the Clinical Imaging Facility and the Trust’s Imaging Department. The Theme also works closely with Imanova in the development of technologies and tracers.
As well as technologies, the BRC supports specialist services for our researchers. The Imperial Clinical Trials Unit provides expertise in clinical trial design, delivery and management. The Patient Experience Research Centre coordinates input from patients and the public in experimental medicine studies, and provides multi-disciplinary support, advice, education and training in developing patient involvement and engagement.
Professor Eric AboagyeTheme Lead, Imaging
Professor Jorge FerrerTheme Lead, Genetics & Genomics
Professor Paul ElliottTheme Lead, Informatics & Biobanking
Dr Jamshid Khorashad
Professor Deborah AshbyChair in Medical Statistics and Clinical Trials and Co-Director, ICTU
Professor Helen WardProfessor of Public Health and Director, PERC
Professor Neil PoulterProfessor of Preventive Cardiovascular Medicine and Co-Director of ICTU