Bioresource for Adult Infectious Diseases (BioAID)

Infectious diseases are a significant problem in the UK. To improve healthcare for patients with infectious diseases, we need to improve our tests to diagnose specific problems and make better predictions about how individual patients may be affected. The Bioresource for Adult Infectious Diseases (BioAID) is an NIHR supported collaborative project that aims to collect biological samples and clinical information from 10,000 episodes in which patients present to hospital with a suspected infectious disease.

Participants will be asked to give consent to have their samples and clinical information collected within BioAID in order to be used to address future studies about how people’s genes and the infectious microbes interact to develop disease. The samples will obtain patients genetic (DNA) code, which will be recorded and stored in a database along with other parts of their blood samples called ‘RNA’ and ‘serum’, and any microbial organisms, which are identified as part of the routine care they receive.

BioAID will provide an invaluable bioresource to evaluate new strategies for diagnosis of infectious diseases and predicting the outcome of specific diseases in individual patients. BioAID will also help to establish the framework for research sampling and data collection to complement existing studies in infectious diseases, and inform the design of new studies as well as the provision of NHS services for infectious diseases. The samples and clinical information collected within BioAID will be held within the participating sites. Access to these collections will be provided to research investigators under the terms of material and data sharing agreements. Identifiable patient information will not be disclosed.

Collaborators

Professor Mahdad Noursadeghi (Chief Investigator)
University College London & University College London Hospitals NHS Trust

Dr Laura Shallcross
University College London & University College London Hospitals NHS Trust

Professor Shiranee Sriskandan
Imperial College & Imperial College Healthcare NHS Trust

Professor Graham Cooke
Imperial College & Imperial College Healthcare NHS Trust

Dr Alex Mentzer
University of Oxford & Oxford University Hospitals NHS Foundation Trust

Dr Martin Gill
Queen Elizabeth Hospital Birmingham

To view study related documents, please use the following links:

Study protocol

Patient information leaflet

Application to access samples

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