This Theme seeks to improve the health of people with metabolic and endocrine diseases. Metabolic diseases, such as obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD) are extremely common. In NW London with a diverse population of 2.4M, there are 1.44M people (60%) who are obese or overweight, 140,000 who have diabetes, and 600,000 (1- in-4) with NAFLD (NW London Health and Care Partnership). The current cost to the NHS of metabolic diseases is £6- 10bn/year (Public Health England). Metabolic disease also affects cardiovascular health (heart attacks, strokes), neurological health (strokes, dementia), kidney disease and infectious disease. For example, the mortality from COVID-19 pandemic respiratory infection is magnified by obesity and diabetes. For endocrine disease, the Theme has a unique focus on infertility/subfertility, which is linked to obesity. This condition affects 1 in 7 couples in the UK and current treatments such as IVF are expensive and difficult to access through the NHS.
Key Individuals
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Dr Tricia Tan
Theme Lead, Metabolic & Endocrine -
Professor Waljit Dhillo
Theme Lead & NIHR Imperial BRC Training Lead -
Dr Bryn Owen
Non-Clinical Lecturer in Endocrinology & Investigative Medicine -
Professor Dominic Withers
Clinical Chair in Diabetes & Endocrinology -
Professor Duncan Bassett
Professor of Endocrinology -
Professor Gary Frost
Chair in Nutrition & Dietetics -
Professor Graham Williams
Clinical Professor of Endocrinology -
Professor Nick Oliver
Wynn Chair in Human Metabolism - Theme Committee Member -
Professor Sir Steve Bloom
Professor of Medicine -
Professor Tony Cass
Professor of Chemistry
