Metabolic & Endocrine

This Theme seeks to improve the health of people with metabolic and endocrine diseases. Metabolic diseases, such as obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD) are extremely common. In NW London with a diverse population of 2.4M, there are 1.44M people (60%) who are obese or overweight, 140,000 who have diabetes, and 600,000 (1- in-4) with NAFLD (NW London Health and Care Partnership). The current cost to the NHS of metabolic diseases is £6- 10bn/year (Public Health England). Metabolic disease also affects cardiovascular health (heart attacks, strokes), neurological health (strokes, dementia), kidney disease and infectious disease. For example, the mortality from COVID-19 pandemic respiratory infection is magnified by obesity and diabetes. For endocrine disease, the Theme has a unique focus on infertility/subfertility, which is linked to obesity. This condition affects 1 in 7 couples in the UK and current treatments such as IVF are expensive and difficult to access through the NHS.

Key Individuals
  • Dr Tricia Tan
    Dr Tricia Tan
    Theme Lead, Metabolic & Endocrine
  • Professor Waljit Dhillo
    Professor Waljit Dhillo
    Theme Lead & NIHR Imperial BRC Training Lead
  • Dr Bryn Owen
    Dr Bryn Owen
    Non-Clinical Lecturer in Endocrinology & Investigative Medicine
  • Professor Dominic Withers
    Professor Dominic Withers
    Clinical Chair in Diabetes & Endocrinology
  • Professor Duncan Bassett
    Professor Duncan Bassett
    Professor of Endocrinology
  • Professor Gary Frost
    Professor Gary Frost
    Chair in Nutrition & Dietetics
  • Professor Graham Williams
    Professor Graham Williams
    Clinical Professor of Endocrinology
  • Professor Nick Oliver
    Professor Nick Oliver
    Wynn Chair in Human Metabolism - Theme Committee Member
  • Professor Sir Steve Bloom
    Professor Sir Steve Bloom
    Professor of Medicine
  • Professor Tony Cass
    Professor Tony Cass
    Professor of Chemistry
Read more + Read less -