Funding CallTraining Digestive Diseases co-funded PhD Studentships

 

The Digestive Diseases Theme have 3 co-funded PhD studentships available – please click the links below to apply – Deadline 15th Jan 24

Leveraging host-microbial metabolite cross-talk to direct precision therapy in inflammatory bowel disease

Led by Prof Nick Powell and Dr Tamas Korcsmaros and co-funded by Astra Zeneca

This PhD project will aim to gain mechanistic insight into the network of microbial proteins and small molecules that drive IBD pathogenesis and regulate responses to IBD therapies.

Identification of novel immunopathological biomarkers of perianal fistulizing Crohn’s disease for improved patient outcomes

Led by Prof Nick Powell and co-funded by Helmsley Charitable Trust

The PhD project aims at defining targetable cellular and molecular interactions driving hallmark features of fistula pathology using advanced computational biology methods to analyse single-cell and spatial transcriptomics data.

Establishing patient-derived organoid reporter systems to facilitate precision medicine and personalised therapies for inflammatory bowel disease

Led by Dr Tamas Korcsmaros and co-funded by the Imperial BRC Organoid Facility

This PhD proposal will aim to gain mechanistic insight into how the changed bile acid composition in the gut impacts epithelial homeostasis in IBD patients. This will uncover novel targets for improving the efficacy of IBD treatment.